Cancer support groups and resources

Having cancer isn’t easy, and when it comes back, it can be even harder. Remember what you can do:

  • Gain knowledge to help you feel in control of your decisions
  • Talk with others who understand what you’re going through

A number of helpful resources and support groups are here for you. These organizations are independent of Jazz Pharmaceuticals.

American Cancer Society®
Everything from emotional support to the latest cancer information. Plus information about support programs in your area.
www.cancer.org

CancerCare®
Free, professional support services for people affected by lung cancer.
www.cancercare.org

Cancer Support Community
Online cancer support, including discussion boards, counselors, blog platforms, and more.
www.cancersupportcommunity.org

GO2 Foundation for Lung Cancer
Dedicated to saving, extending, and improving the lives of people with lung cancer.
www.go2foundation.org

LUNGevity
Information, resources, and ways to connect with patients, caregivers, and medical experts.
www.lungevity.org

Lung Cancer Research Foundation®
Educational materials and a lung cancer support line.
www.lungcancerresearchfoundation.org

Lung Cancer Foundation of America
A resource for patients seeking answers, hope, and access to updated treatment information.
www.lcfamerica.org

All product names and brands are property of their respective owners.

For handy access to the
Patient Brochure for ZEPZELCA,

WHAT IS ZEPZELCA?

ZEPZELCA™ (lurbinectedin) is a prescription medicine used to treat adults with a kind of lung cancer called small cell lung cancer (SCLC).

ZEPZELCA may be used when your lung cancer:

  • has spread to other parts of the body (metastatic), and
  • you have received treatment with chemotherapy that contains platinum, and it did not work or is no longer working.

ZEPZELCA is approved based on response rate and how long the response lasted. Additional studies will further evaluate the benefit of ZEPZELCA for this use.

Important safety Information

Before receiving ZEPZELCA, tell your healthcare provider about all of your medical conditions, including if you:

  • have liver or kidney problems.
  • are pregnant or plan to become pregnant. ZEPZELCA can harm your unborn baby.
  • Females who are able to become pregnant:
    • Your healthcare provider should do a pregnancy test before you start treatment with ZEPZELCA.
    • You should use effective birth control (contraception) during treatment with and for 6 months after your final dose of ZEPZELCA.
    • Tell your healthcare provider right away if you become pregnant or think that you are pregnant during treatment with ZEPZELCA.
    Males with female partners who are able to become pregnant should use effective birth control during treatment with and for 4 months after your final dose of ZEPZELCA.
  • are breastfeeding or plan to breastfeed. It is not known if ZEPZELCA passes into your breastmilk. Do not breastfeed during treatment with ZEPZELCA and for 2 weeks after your final dose of ZEPZELCA. Talk to your healthcare provider about the best way to feed your baby during treatment with ZEPZELCA.
  • Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Certain other medicines may affect how ZEPZELCA works.

What should I avoid while using ZEPZELCA?

Avoid eating or drinking grapefruit, or products that contain grapefruit juice during treatment with ZEPZELCA.

ZEPZELCA can cause serious side effects, including:

  • Low blood cell counts. Low blood counts including low neutrophil counts (neutropenia) and low platelet counts (thrombocytopenia) are common with ZEPZELCA, and can also be severe. Some people with low white blood cell counts may get fever, or an infection throughout the body (sepsis), that can cause death. Your healthcare provider should do blood tests before you receive each treatment with ZEPZELCA to check your blood cell counts.
  • Tell your healthcare provider right away if you develop:
    • fever or any other signs of infection
    • unusual bruising or bleeding
    • tiredness
    • pale colored skin
  • Liver problems. Increased liver function tests are common with ZEPZELCA, and can also be severe. Your healthcare provider should do blood tests to check your liver function before you start and during treatment with ZEPZELCA.
  • Tell your healthcare provider right away if you develop symptoms of liver problems including:
    • loss of appetite
    • nausea or vomiting
    • pain on the right side of your stomach area (abdomen)
    Your healthcare provider may temporarily stop treatment, lower your dose, or permanently stop ZEPZELCA if you develop low blood cell counts or liver problems during treatment with ZEPZELCA.

The most common side effects of ZEPZELCA include:

  • tiredness
  • low white and red blood cell counts
  • increased kidney function blood test (creatinine)
  • increased liver function blood tests
  • increased blood sugar (glucose)
  • nausea
  • decreased appetite
  • muscle and joint (musculoskeletal) pain
  • low level of albumin in the blood
  • constipation
  • trouble breathing
  • low levels of sodium and magnesium in the blood
  • vomiting
  • cough
  • diarrhea

These are not all of the possible side effects of ZEPZELCA.

Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088. You may also report side effects to Jazz Pharmaceuticals at 1-800-520-5568.

Please see accompanying full Prescribing Information including Patient Information, and discuss with your doctor.

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Important safety Information

Before receiving ZEPZELCA, tell your healthcare provider about all of your medical conditions, including if you:

  • have liver or kidney problems.
  • are pregnant or plan to become pregnant. ZEPZELCA can harm your unborn baby.